Hafiz M. N. Iqbal, Angel M.V. Rodriguez, Rekha Khandia, Ashok Munjal and Kuldeep Dhama Pages 86 - 93 ( 8 )
Background: In the recent past, a wider spectrum of nanotechnologybased drugs or drug-loaded devices and systems has been engineered and investigated with high interests.Objective: The key objective is to help for an enhanced/better quality of patient life in a secure way by avoiding/limiting drug abuse, or severe adverse effects of some in practice traditional therapies. Method: Various methodological approaches including in vitro, in vivo, and ex vivo techniques have been exploited, so far. Among them, nanoparticles-based therapeutic agents are of supreme interests for an enhanced and efficient delivery in the current biomedical sector of the modern world. Results: The development of new types of novel, effective and highly reliable therapeutic drug delivery system (DDS) for multipurpose applications is essential and a core demand to tackle many human health related diseases. In this context, nanotechnology-based several advanced DDS have been engineered with novel characteristics for biomedical, pharmaceutical and cosmeceutical applications that include but not limited to the enhanced/improved bioactivity, bioavailability, drug efficacy, targeted delivery, and therapeutically safer with an extra advantage of overcoming demerits of traditional drug formulations/designs. This review work is focused on recent trends/advances in nanotechnology-based drugs and formulations designed for targeted therapeutic delivery. Moreover, information is also reviewed and given from recent patents and summarized or illustrated diagrammatically to depict a better understanding. Recent patents covering various nanotechnology-based approaches for several applications have also been reviewed. Conclusion: The drug-loaded nanoparticles are among versatile candidates with multifunctional characteristics for potential applications in biomedical, and tissue engineering sector.
Biomaterials, biomedical sector, drug delivery, drug-loaded nanoparticles, nanotechnology, therapeutic approaches.
ENCIT - Science, Engineering and Technology School, Tecnologico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, ENCIT - Science, Engineering and Technology School, Tecnologico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, Department of Biochemistry and Genetics, Barkatullah University, Bhopal-462 026 (MP), Department of Biochemistry and Genetics, Barkatullah University, Bhopal-462 026 (MP), Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, Uttar Pradesh